CEO Shin Yoshida Presented at “LUX FORUM TOKYO”

Our CEO, Shin Yoshida, delivered a pitch presentation at “LUX FORUM TOKYO – The Future of Materials Innovation”, hosted by Lux Research Inc. on Tuesday, November 11, 2025.

This forum is recognized as a premier event that brings together companies, researchers, and startups from around the world to discuss the latest trends and innovations in materials science, chemistry, and biomaterials. The event was highly engaging, and our presentation on bio-manufacturing enabled by our zwitterionic hydrogel technology attracted strong interest from many participants.

The venue was vibrant throughout the day, with numerous companies expressing significant interest in our platform technologies. We will continue to follow up with those we connected with. If we were unable to speak with you during the event, we would be grateful to hear from you directly.

Presentation at the 94th Symposium of Japanese Society of Enzyme Engineering

We will present a poster at the 94th Symposium of Japanese Society of Enzyme Engineering, to be held on Friday, November 21, 2025, at Digital Multi-Purpose Hall, Institute of Science Tokyo.

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Title：Enhancement of Enzyme Thermal Stability with a Zwitterionic Polymer Hydrogel

Presenters: Satoshi Yamashita*, Shin Yoshida, and Madoka Takai

Our developed zwitterionic polymer is a novel hydrogel material that combines excellent biocompatibility with a strong enzyme-stabilizing effect, making it promising for a wide range of applications. In this study, we report that simply mixing the polymer with enzymes—without any chemical bonding—significantly enhances their thermal stability, outperforming conventional stabilizers such as polysaccharides and PEG. In particular, experiments with β-galactosidase demonstrated that enzyme activity was maintained while thermal deactivation under high-temperature conditions was effectively suppressed. These findings indicate that our zwitterionic polymer functions as an efficient additive for maintaining enzyme activity over extended periods, offering great potential for applications in the food, pharmaceutical, and biomanufacturing industries.

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Title: Immobilization of enzymes with zwitterionic polymer hydrogels and their applications

Presenters: Maki Itoh*, Yuya Fukui, Shin Yoshida, and Madoka Takai

Our hydrogels based on polymers containing zwitterionic groups are attracting attention in various applications, due to their biocompatibility. Characteristics including thermal stability and durability to proteases were improved by covalently bonding enzymes to the hydrogel polymers. Immobilization of the bonded polymer-enzyme conjugates onto inorganic particles enabled repeated use of the enzyme, which was not easy with non-conjugated enzymes. Compared with traditional particle immobilization approaches, including physical adsorption and chemical linking of just enzymes, use of the hydrogels allowed to keep high activity in repeated use.

CEO Shin Yoshida to Speak at Symposium of The Science Research Committee for Water and Future Living on November 17

Our CEO, Shin Yoshida, will give a presentation at The Science Research Committee for Water and Future Living on Monday, November 17, 2025.This research committee is based on a decade of study on future living and water by the former 183^rd Committee of the Japan Society for the Promotion of Science.

During the startup session at this event, our CEO will give a presentation titled “Functionalization and Application of Biomaterials Using Zwitterionic Hydrogels”, introducing the unique features and potential of our hydrogel technology.

[Event Details］

Date & Time: Monday, November 17, 2025, 3:00 p.m. – 3:20 p.m

Host: The Science Research Committee for Water and Future Living

Presentation Title: Functionalization and Application of Biomaterials Using Zwitterionic Hydrogels

Venue:2nd Floor, Room 1, Morito Memorial Hall, Tokyo University of Science

Official Website: The Science Research Committee for Water and Future Living